Adventurer and geneticist: Spencer Wells

A very good interview with geneticist Spencer Wells about his Genographic Project at PlosGenetics. He says about Hungary:

We've gotten some fascinating results and a lot of e-mails. For example, a Hungarian woman wrote in and said, “You've got to redo my test. You told me I'm native American or Siberian, and I know my ancestors came from Hungary—I can tell you the village they were living in in the sixteenth century.” The Hungarian language, Magyar, is actually related to languages spoken in Siberia, and this is one of the first cases where we've actually seen Siberian lineages showing up in the Hungarian population. They are there at very low frequency. We now through this project have over 350 people who are of Hungarian descent and we see these [Siberian] lineages at four to five percent on both male and female sides.

And he says about the traditional tribal genealogical thinking (here in southern Tajikistan):

... Most people are interested in their history, and indigenous people, who are the ones who give us the clearest glimpse of their genetic history, are particularly interested, because in many cases it is all they have—what they cling on to—their sense of identity.

I was just in Tajikistan a week and a half ago, and we were sampling all over the southern part of the country and asking people to name their grandparents and great-grandparents and so on. I could do that back to maybe to my great-grandparents. These people can do it back six, seven, eight generations. They've always lived in the same place and beyond that they know even more about their history, but not necessarily their names.

So they have a sense, a clear idea of where they came from, that something is passed from generation that ties them to their ancestors. You explain to them that that thing is DNA and that it will tell us not only about the people they can name but also people beyond that that they can't name ...

Some personal things about this blonde Spencer Wells:

My father (...) he comes from a military family. His father, whom he never knew because he died in World War II, graduated top of his class from West Point and was apparently a wild man out in the field. I think maybe I got some of my love of danger and going to strange places from him. ...

The Anglo-Saxons ... Genes, Mind and Culture ....

Nicholas Wade gives a good survey in the NYT about current thinking of geneticists about the population history of the British Isles since their recolonization after the Ice-Age. Geneticists seem to agree, that most of current people in the British Isle are stemming from this recolonization after the Ice-Age and not from later migrations bringing agriculture (4000 BC) or by the Celts, the Anglo-Saxons or the Vikings. (But Bryan Sykes seems to make greater differences between small neolithic and big celtic genetic influence on current populations.)

The geneticists Stephen Oppenheimer, Bryan Sykes, Christopher Tyler-Smith, Mark Thomas, Peter Forster and others mostly disagree at the moment about the Anglo-Saxonian genetical influence. And there is another - may be - new insight:

English is usually assumed to have developed in England, from the language of the Angles and Saxons, about 1,500 years ago. But Forster argues that the Angles and the Saxons were both really Viking peoples who began raiding Britain ahead of the accepted historical schedule. They did not bring their language to England because English, in his view, was already spoken there, probably introduced before the arrival of the Romans by tribes such as the Belgae, whom Caesar describes as being present on both sides of the Channel. (...)

Germanic is usually assumed to have split into three branches: West Germanic, which includes German and Dutch; East Germanic, the language of the Goths and Vandals; and North Germanic, consisting of the Scandinavian languages. Forster's analysis shows English is not an offshoot of West Germanic, as usually assumed, but is a branch independent of the other three, which also implies a greater antiquity. Germanic split into its four branches some 2,000 to 6,000 years ago, Forster estimates.

Addendum: Razib Khan and others are sceptical concerning the last thoughts. Me too. But you should never say never.

Beginning of agriculture in China by migrations from Europe?

Last year in the journal "Archäologie in Deutschland" there were given hints by Detlef Gronenborn (pdf., german language), that archaeological connections exist between the first european farmers (the Linearbandkeramiker) and new detected archaeological cultures in Russia (Elshan-Culture) and Northern China. (More from Detlef Gronenborn here - also in English.)

Now it seems that we have ancient genetic data for this connections as well. And that would mean, that these connections were'nt only cultural but also genetic. This would be a very great surprise.

The Phylogeography of Haplogroup N1a

Gokcumen O et al.

Recent studies have revealed a complex geographic distribution of haplogroup N1a. This rare and distinctive lineage is widely distributed across Eurasia and Africa, but always found at very low frequencies. However, despite its rarity, the genetic diversity within N1a has remained relatively high (h=0.9605). The reduced median network of N1a haplotypes not only reflects this level of diversity, but also exhibits several relatively well-defined branches. The distribution of N1a is intriguing because of revealing previously unrecognized connections between populations. What makes N1a even more interesting is the prevalence of this lineage in ancient European populations. Haak et al. (2005) found that 25% of their European Neolithic samples belonged to N1a and dated to ~5000 BCE, whereas the frequency of this lineage in contemporary Europeans is only ~0.2%. In addition, an Iron Age skeleton from Kazakhstan had an N1a haplotype, suggesting the existence of this lineage in the Altai Republic in ~500BCE (Ricaut et al. 2004). Indeed, we found several haplogroup N1a mtDNAs in indigenous Altaians and Altaian Kazakhs. To further elucidate the phylogeography of this lineage in Central Asia, we sequenced the whole mtDNA genomes of our N1a haplotypes, and analyzed the resulting data with several quantitative methods and simulation programs to estimate their expansion times and spatial distribution in Eurasia. Our findings suggest that there are two well-defined sublineages within N1a, and that the dispersal of this haplogroup could be associated with the Neolithic expansion and with prehistoric interactions between Central Asian and European populations.

Population bottleneck during "out of africa"

New hints for a population bottleneck concerning (anatomical modern) humans leaving the african continent were presented in "Annals of Human Genetics":

"... At the NF1 gene locus two clearly separated groups of haplotypes, corresponding to the two haplogroups described by us (Schmegner et al. 2005), are present in the European population and both Asian populations, but not in the African population. This argues against a population bottleneck during the immigration of the AMH into Europe, because a reduction to two NF1 gene lineages during this event would not have affected the Asian populations. At the chromosome 22 locus a different picture is obtained for the European and Asian populations, with no split into two clearly separated subgroups of haplotypes. The patterns for the two loci in the African population are quite similar. Therefore, if a population bottleneck is considered to explain the variability patterns, the HapMap data show that this bottleneck most probably occurred throughout the emigration of the AMH out of Africa. Recently signs of a population bottleneck in variability data obtained for a number of genomic loci in European and Asian populations, but not in African populations, were described and also led to the conclusion that this bottleneck occurred after the appearance of the AMH in Africa, and thus presumably during the emigration out of Africa (Harpending & Rogers, 2000; Balciuniene et al. 2001; Alonso & Armour, 2004; Marth et al. 2004; Stajich & Hahn, 2005; Voight et al. 2005)."

And for Europe only:

"Regarding demography, the most plausible explanation is the assumption of a severe bottleneck in the history of the European population: in the case of the chromosome 17 locus two ancient lineages passed this bottleneck; for the chromosome 22 locus it was only one ancient lineage."